So I am building a high gain live rig and need some suggestions. I used to have quite a few different amp heads and fx units a few years ago when I was playing live in bands etc... I stopped playing live for a few years and went to a Axe FX based rig to use in my studio. While that's been great, I am looking to start gigging again and playing in a live band situation and want to build a live rig again which is based around a real high gain tube amp. HOWEVER while I LOVE the sound of a real amp and my rigs in the past have always sounded great, what I do not miss is the Russian roulette game of buying bits of gear and hoping that they play nice with each other especially regarding ground loop hums in the FX loop of a high gain amp. As far as I can remember ALL my previous guitar rigs were plagued with this problem despite me doing everything to try to avoid this. The great thing about my Axe FX is that you can chain a million virtual things together inside the unit and everything is silence... not like that in the real world however. SO I am wondering if people can tell me a bit about their experiences with high gain heads these days, and if they are using them with digital multi FX units in the FX loop without getting ground loop problems. I am interested to know what amps and fx units ppl are using. I am basically looking for a good high gain amp + 1 digital multi FX unit which has at least an EQ block and a noise gate block.