I have a UX8 and had all sorts of issues with windows 7. There were audio drop outs, pops, and clicks during play back and recording. I tried everything imaginable but ended up just going to a dual boot system with my recording software on the drive with XP. Hopefully there is a more compatible driver released in the future. You can also go to the Line 6 forum and have them start a "support ticket" but you can imagine how good their support is  Good luck.
Six's:
Gibson Les Paul Studio
ESP LTD EC-1000 - EMG 81/81
Fender Strat - Duncan Blackout/Mick Thompson Blackout, tricked the .... out.
Seven's:
Ibanez RG7321 - JB/Jazz w/Blackouts Modular Preamp.
ESP LTD M-107 tricked the .... out.
ERG's:
ESP LTD VB-400 Viper Baritone - Blackout/EMG 85
Ibanez RGA8 - D Activator 8's
Amp stuff:
Axe FX Ultra
Mesa Oversized 4x12
Line 6 Vetta HD
Framus Dragon 4x12
Basses:
Fender Jazz Bass - EMG's
Schecter Elite 4 Bass - EMG/BQC Control.
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