I have a UX8 and had all sorts of issues with windows 7. There were audio drop outs, pops, and clicks during play back and recording. I tried everything imaginable but ended up just going to a dual boot system with my recording software on the drive with XP. Hopefully there is a more compatible driver released in the future. You can also go to the Line 6 forum and have them start a "support ticket" but you can imagine how good their support is
Gibson Les Paul Studio
ESP LTD EC-1000 - EMG 81/81
Fender Strat - Duncan Blackout/Mick Thompson Blackout, tricked out.
Ibanez RG7321 - Blaze/Jazz w/Blackouts Modular Preamp.
ESP LTD M-107 tricked out.
ESP LTD VB-400 Viper Baritone - Blackout/EMG 85
Ibanez RGA8 - D Activator 8's
Axe FX Ultra
Mesa Oversized 4x12
Line 6 Vetta HD
Framus Dragon 4x12
Fender Jazz Bass - EMG's
Schecter Elite 4 Bass - EMG/BQC Control.